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王平平

发布者:  时间:2023-11-14  浏览:

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王平平,教授,硕士生导师,主要从事复杂疾病的免疫信息学研究,主持科技部国家重点研发计划子课题1项、国家自然基金委重大项目子课题1项,参与国家自然科学基金委重点、杰青、优青、面上、新冠应急专项等项目,在复杂疾病免疫信息学方向取得了一系列研究成果,以第一或通讯作者身份在cell、cell discovery、protein cell、clinical and translational medicine、nucleic acids research、briefings in bioinformatics、bioinformatics等国际权威期刊上发表sci论文16篇, 1篇入选2019年度“中国百篇最具影响国际学术论文”,1篇入选2021年度“中国生物信息学十大进展”。授权软件著作权1项,申请发明专利2项。

教育经历

2018.03 2022.07    哈尔滨工业大学            生物医学工程 博士

2011.09 – 2014.06    中国科学院大学            生物工程 硕士

2006.09 – 2011.06    哈尔滨医科大学            生物技术(生物信息学方向)  学士

工作经历

2022.11 - 至今          哈尔滨医科大学           医工交叉学院      教授

2017.01 - 2017.12     黑龙江水产研究所 遗传育种与生物技术研究室 助理研究员

2014.07 - 2016.12     黑龙江水产研究所 遗传育种与生物技术研究室 研究实习员

科研项目

1. 科学技术部,国家重点研发计划,数据驱动的人脑多尺度数字孪生关键理论与技术,2024-01-01至2026-12-3179.9万,子课题负责人

2. 国家自然科学基金委员会,重大项目,腔内肿瘤光学多模态诊疗一体化研究, 2023-01-01 2027-12-31100万,子课题负责人

代表性论文

1. pingping wang, lifen yao, meng luo, wenyang zhou, xiyun jin, zhaochun xu, shi yan, yiqun li, chang xu, rui cheng, yan huang, xiaoyu lin, kexin ma, huimin cao, hongxin liu, guangfu xue, fang han, huan nie, qinghua jiang*. single-cell transcriptome and tcr profiling reveal activated and expanded t cell populations in parkinson's disease. cell discovery. 2021. 7(1): 52. (sci if=33.5)

2. pingping wang, zhaochun xu, wenyang zhou, xiyun jin, chang xu, meng luo, kexin ma, huimin cao, yan huang, xiaoyu lin, fenglan pang, yiqun li, qinghua jiang*. identification of potential vaccine targets for sars-cov-2 by combining single-cell and bulk tcr sequencing. clinical and translational medicine. 2021. 11(5): e430. (sci if=10.6)

3. pingping wang, meng luo, wenyang zhou, xiyun jin, zhaochun xu, shi yan, yiqun li, chang xu, rui cheng, yan huang, xiaoyu lin, lifen yao*, huan nie*, qinghua jiang*. global characterization of peripheral b cells in parkinson’s disease by single-cell rna and bcr sequencing. frontiers in immunology. 2022. 13: 1664-3224. (sci if=7.3)

4. pingping wang, xiyun jin, wenyang zhou, meng luo, zhaochun xu, chang xu, yiqun li, kexin ma, huimin cao, yan huang, guangfu xue, shuilin jin, huan nie*, qinghua jiang*. comprehensive analysis of tcr repertoire in covid-19 using single cell sequencing. genomics. 2021. 113(2): 456-462. (sci if=4.4)

5. pingping wang, le wang, jian yang, peixian luan, xiaofeng zhang, youyi kuang*, xiaowen sun*. sex-biased mirnas of yellow catfish (pelteobagrus fulvidraco) and their potential role in reproductive development. aquaculture. 2018. 485, 73-80. (sci if=4.5)

6. pingping wang, min zheng, jian liu, yongzhuang liu, jianguo lu*, xiaowen sun. sexually dimorphic gene expression associated with growth and reproduction of tongue sole (cynoglossus semilaevis) revealed by brain transcriptome analysis. international journal of molecular sciences. 2016. 17. (sci if=5.6)

7. fang li#, meng luo#, wenyang zhou#, jinliang li, xiyun jin, zhaochun xu, liran juan, zheng zhang, yuou li, renqiang liu, yiqun li, chang xu, kexin ma, huimin cao, jingwei wang, pingping wang*, zhigao bu*, qinghua jiang*. single cell rna and immune repertoire profiling of covid-19 patients reveal novel neutralizing antibody. protein cell. 2021. 12(10): 751-755 (sci if=21.1)

8. shihua zhang#, cheng zhang#, jinke du, rui zhang, shixiong yang, bo li, pingping wang* and wensheng deng*. prediction of lymph-node metastasis in cancers using differentially expressed mrna and non-coding rna signatures. frontiers in cell and developmental biology. 2021. 9, 605977. (sci if=5.5)

9. xianwen ren#, wen wen#, xiaoying fan#, wenhong hou#, bin su#, pengfei cai#, jiesheng li#, yang liu#, fei tang#, fan zhang#, yu yang#, jiangping he#, wenji ma#, jingjing he#, pingping wang#, qiqi cao, fangjin chen, yuqing chen, xuelian cheng, guohong deng, xilong deng, wenyu ding, yingmei feng, rui gan, chuang guo, weiqiang guo, shuai he, chen jiang, juanran liang, yi-min li, jun lin, yun ling, haofei liu, jianwei liu, nianping liu, shu-qiang liu, meng luo, qiang ma, qibing song, wujianan sun, gaoxiang wang, feng wang, ying wang, xiaofeng wen, qian wu, gang xu, xiaowei xie, xinxin xiong, xudong xing, hao xu, chonghai yin, dongdong yu, kezhuo yu, jin yuan, biao zhang, peipei zhang, tong zhang, jincun zhao, peidong zhao, jianfeng zhou, wei zhou, sujuan zhong, xiaosong zhong, shuye zhang, lin zhu, ping zhu, bin zou, jiahua zou, zengtao zuo, fan bai 1, xi huang, penghui zhou*, qinghua jiang*, zhiwei huang*, jin-xin bei*, lai wei*, xiu-wu bian*, xindong liu*, tao cheng*, xiangpan li*, pingsen zhao*, fu-sheng wang*, hongyang wang*, bing su*, zheng zhang*, kun qu*, xiaoqun wang*, jiekai chen*, ronghua jin*, zemin zhang*. covid-19 immune features revealed by a large-scale single cell transcriptome atlas. cell. 2021. 184(7): 1895-1913. (sci if=64.5)

10. liang cheng#, pingping wang#, rui tian #, song wang, qinghua guo, meng luo,wenyang zhou, guiyou liu, huijie jiang*,and qinghua jiang*.lncrna2target v2.0: a comprehensive database for target genes of lncrnas in human and mouse. nucleic acids research. 2019. 47, d140-d144. (sci if=14.9)

11. yan huang#, pingping wang#, wenyang zhou, meng luo, zhaochun xu, rui cheng, chang xu, xiyun jin, yiqun li and qinghua jiang. comprehensive analysis of partial methylation domains in colorectal cancer based on single-cell methylation profiles. briefings in bioinformatics. 2021. 22. (sci if=9.5)

12. zhibin lv#, pingping wang#, quan zou* and qinghua jiang*. identification of sub-golgi protein localization by use of deep representation learning features. bioinformatics. 2020. 36, 5600-5609. (sci if=5.8)

13. yansu wang#, pingping wang#, yingjie guo, shan huang, yu chen* and lei xu*. prpred:a predictor to identify plant resistance proteins by incorporating k-spaced amino acid (group) pairs. frontiers in bioengineering and biotechnology. 2020. 8, 645520. (sci if=5.7)

14. wenyi yang#, pingping wang#, meng luo, yideng cai, chang xu, guangfu xue, xiyun jin, rui cheng, jinhao que, fenglan pang, yuexin yang, huan nie, qinghua jiang*, zhigang liu*, zhaochun xu*. deepcci: a deep learning framework for identifying cell–cell interactions from single-cell rna sequencing data. bioinformatics. 2023, 39(10). (sci if=5.8)

15. xiaoxia ying#, xiyun jin#, pingping wang#, yuzhu he, haomiao zhang, xiang ren,songling chai, wenqi fu, pengcheng zhao, chen chen, guowu ma* and huiying liu*. integrative analysis for elucidating transcriptomics landscapes of glucocorticoid-induced osteoporosis. frontiers in cell and developmental biology. 2020. 8, 252. (sci if=5.5)

16. hui dong#, wenyang zhou#, pingping wang#, enjun zuo, xiaoxia ying,songling chai, tao fei, laidi jin, chen chen, guowu ma and huiying liu*.comprehensive analysis of the genetic and epigenetic mechanisms of osteoporosis and bone mineral density. frontiers in cell and developmental biology. 2020. 8, 194. (sci if=5.5)

获奖情况

1. 王平平,2022,哈尔滨工业大学优秀毕业生

2. 王平平2011,黑龙江省级优秀毕业生

3. 王平平2011,哈尔滨医科大学优秀毕业生

4. 王平平。mirna测序数据分析软件。软件著作权:2018sr1982392018323日。

5. 蒋庆华,王平平,步志高,赵东明。基于单细胞测序与混合细胞bcr测序联合的病毒中和抗体筛选方法及新冠病毒中和抗体序列gd1-69。中国专利:202011437419.520201215日。

6. 蒋庆华,许召春,王平平,周文洋。一种融合了单细胞tcr测序数据的肿瘤新生抗原筛选方法。中国专利:zl202110443345.42022614日。

名:王平平

职称职务:教授

                 硕士生导师

研究方向:生物医学信息学

免疫信息学

e-mail:wangpingping@hrbmu.edu.cn



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